October 15，2025

Congrats to Yuyang Su et al. for the latest publication in J. Am. Chem. Soc. We demonstrate a nickel-catalytic system that achieves the regioselective double hydroboration of unsymmetrical internal alkynes with pinacolborane (HBpin), enabling efficient synthesis of sterically congested quaternary 1,1-diboryl alkanes. Mechanistic studies reveal that the catalytic activity originates from in situ-generated Ni nanoclusters, which uniquely activate multiple HBpin simultaneously and enable geminal (H, H) and (B, B) addition to alkynes.