研究进展简报

生命有机化学国家重点实验室瞿旭东副研究员（刘文课题组）等在Angew杂志发表研究论文：

http://onlinelibrary.wiley.com/doi/10.1002/anie.201103085/pdf

Transcriptome mining of active biosynthetic pathways and their associated products in Streptomyces flaveolus

Xudong Qu, Chun Lei and Wen Liu

Angew. Chem. Int. Ed. 2011, 50, 9651-9654

Transcriptome mining of active biosynthetic pathways with their associated (known and unknown) products was achieved in Streptomyces flaveolus at the transcriptional level, where a key linkage of converting the genotype to the chemotype exists. This approach complements recent advances in genome mining and potentially benefits natural product discovery from strains whose genomes have not been sequenced.